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Wnt signaling pathway: Quiz

  

Question 1: Other proteins including prickle, strabismus, ________ and rho-kinase act downstream of frizzled and dishevelled to regulate the cytoskeleton and planar cell polarity.
RHOARAC1CDC42RHOB

Question 2: The Wnt signaling pathway describes a network of proteins most well known for their roles in embryogenesis and ________, but also involved in normal physiological processes in adult animals.
CarcinogenesisChemotherapyMetastasisCancer

Question 3: ________ (Secreted Frizzled Protein) is a regulator of Wnt.
Secreted frizzled-related protein 1Beta-cateninFZD6Lymphoid enhancer-binding factor 1

Question 4: ________ - A curated resource of signal transduction pathways in humans
Johns Hopkins UniversityBioinformaticsInterleukin 2Netpath

Question 5: Researchers at Stanford School of Medicine observed that embryoid bodies spontaneously begin ________.
ArchenteronGastrulationRegional specificationCleavage (embryo)

Question 6: The Wnt pathway involves a large number of proteins that can regulate the production of Wnt signaling molecules, their interactions with receptors on target cells and the physiological responses of target cells that result from the exposure of cells to the extracellular Wnt ________.
Crystal field theoryLigandCoordination complexHSAB theory

Question 7: The Wnt Pathway (also the Hedgehog and Notch pathways) are thought to be involved in the occurrence of ________ (CSC).
Adult stem cellCellular differentiationStem cell treatmentsCancer stem cell

Question 8: The wingless gene had originally been identified as a recessive mutation affecting wing and haltere development in ________[3].
Model organismInsectCaenorhabditis elegansDrosophila melanogaster

Question 9: It was subsequently characterized as segment polarity gene in ________ that functions during embryogenesis[4] and also during adult limb formation during metamorphosis.
Model organismInsectCaenorhabditis elegansDrosophila melanogaster

Question 10: Protein homology suggests that several distinct Wnt ligands were present in the common ancestor of all bilaterian life, and certain aspects of Wnt signaling are present in sponges and even in ________.
Slime moldAscomycotaPlantAmoebozoa
















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