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Venlafaxine: Quiz

  
  

Question 1:
What is the chemical name of Venlafaxine (IUPAC)
{(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yloxy}-
-1-2-dimethylamino-1-(4-methoxyphenyl)-ethylcyclohexanol
3-(dimethylamino)-1-hydroxypropane-1,1-diylbis
6-dimethylamino-4,4-diheptan-3-ol

Question 2: The neurotransmitters affected are serotonin (5-hydroxytryptamine) and ________ (noradrenaline).
NorepinephrinePhenethylamineTyramineOctopamine

Question 3:
How is Venlafaxine excreted?
N/A
Renal: 93%
Renal
Biliary, renal

Question 4: [3] The ________ of venlafaxine is relatively short, and, therefore, patients are directed to adhere to a strict medication routine, avoiding missing a dose.
Cosmic rayNuclear fissionRadioactive decayHalf-life

Question 5: A report in the ________ in 2002 by Dr.
Peer reviewBMJOpen access (publishing)The Lancet

Question 6:
What is the elimination half life of Venlafaxine?
1 g dose: 5 h
5.4 u00B1 1.0 hours after IM or IV administration
5 u00B1 2 h ; 11 u00B1 2 h
< 2 h

Question 7: It should not be taken by anyone who is allergic to the inactive ingredients, which include gelatin, ________, ethylcellulose, iron oxide, titanium dioxide and hypromellose.
CelluloseGlucoseStarchSucrose

Question 8: Administration of ________ can prevent absorption of the drug.
CarbonPoisonChelation therapyActivated carbon

Question 9: It should never be used with a ________ (MAOI), as it can cause potentially deadly serotonin syndrome.
Monoamine oxidase inhibitorPardoprunoxTetracyclic antidepressantTricyclic antidepressant

Question 10: The FDA asked the manufacturers of all SNRIs to include the risk of persistent ________ (PPHN) in prescribing data as of July 19, 2006.
Pulmonary hypertensionPulmonary embolismPneumoniaChylothorax
















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