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Vancomycin: Quiz


Question 1:
What is the elimination half life of Vancomycin?
2u20133 hours
4 to 5 hours
6-10 days
7 to 14 hours

Question 2: Lately it has been emphasized that vancomycin can induce platelet-reactive antibodies in the patient, leading to severe ________ and bleeding with florid petechial hemorrhages, ecchymoses, and wet purpura.
Idiopathic thrombocytopenic purpuraAplastic anemiaThrombotic thrombocytopenic purpuraThrombocytopenia

Question 3: ________ agents, excluding corticosteroids (Cromoglicic acid)
Immune systemCell-mediated immunityAutoimmunityAllergen

Question 4: The development and use of novel antibiotics such as linezolid and ________ is expected to delay, but not halt, the emergence of bacteria resistant to all available antibiotics.

Question 5:
What is the molecular weight of Vancomycin?
358.842 g/mol
321.456 g/mol
1449.3 g.mol-1

Question 6:
How is Vancomycin excreted?
faecal 47%
Urine, within 24 hours

Question 7: Subsequent reviews of accumulated case reports of vancomycin-related nephrotoxicity found that many of the patients had also received other known nephrotoxins, particularly ________.

Question 8: Less frequently, hypotension and ________ may also occur.

Question 9: Vancomycin (INN) (pronounced /ˌvæŋkɵˈmaɪsɪn/) is a glycopeptide ________ used in the prophylaxis and treatment of infections caused by Gram-positive bacteria.
ATC code J01Antibiotic misuseNucleic acid inhibitorAntibiotic

Question 10: Nonribosomal peptide synthesis occurs through distinct modules that can load and extend the protein by one amino acid through the ________ bond formation at the contact sites of the activating domains.

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