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Valproate semisodium: Quiz


Question 1: It is used in the UK, Canada, and U.S. for the treatment of the manic episodes of ________.
PsychosisSchizoaffective disorderMajor depressive disorderBipolar disorder

Question 2: These suggest a possibility of ________ damage.
Immune systemLiverPancreasEndocrine system

Question 3: United StatesDepakote and Depakote ER (Extended Release) by ________
Aon CorporationAbbott LaboratoriesBoeingMcDonald's

Question 4: ________Depakote by Sanofi-Aventis
CanadaEnglandWalesUnited Kingdom

Question 5: It is about five times the price of sodium valproate, which has been marketed for around 30 years as Epilim by the same company for ________ and is also available from other manufacturers as a generic product.
Generalised epilepsyPartial seizureEpilepsyLafora disease

Question 6: ________Ergenyl Chrono by Sanofi-Aventis and generics

Question 7: It is also used in the US for the treatment of epilepsy, ________ associated with neuropathy, and migraine headaches.
Pain managementChronic painPain scaleLow back pain

Question 8: In rare cases, it is also used as a treatment for major depressive disorder, and increasingly taken long-term for prevention of both manic and ________ phases of bipolar disorder, especially the rapid-cycling variant.
Mood disorderSchizoaffective disorderPsychosisMajor depressive disorder

Question 9: The most severe side effects are ten times higher-than-average incidence rates of serious, irreversible birth defects (teratogenic) such as births of brainless babies (________).
HoloprosencephalyDandy-Walker syndromeSpina bifidaAnencephaly

Question 10: Some serious side effects are unusual bleeding (especially in the urine), ________, and complete drowsiness.
HallucinationSuicidal ideationHypersomniaAuditory hallucination

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