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Tolcapone: Quiz


Question 1: Tolcapone is a yellow, odorless, non-hygroscopic, ________ compound with a relative molecular mass of 273.25.
SolidCrystal structureCrystalCarbon

Question 2: Tolcapone has the ability to cross the ________ and thus exerts its COMT inhibitory effects in the CNS as well as in the periphery.
Blood-brain barrierMeningitisAIDSImmune system

Question 3: Tolcapone is a ________ that inhibits the enzyme catechol-O-methyl transferase (COMT).
MDMAPhencyclidinePsychoactive drugDrug

Question 4: Tolcapone has demonstrated significant ________[2] that limits the drug's therapeutic utility to a drug of last resort.
AspirinHepatitisHepatotoxicityAcute liver failure


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