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Talin protein: Quiz


Question 1: A structure-function analysis reported recently[19] provides a cogent structural model (see top right) to explain talin-dependent ________ activation in three steps:
Talin proteinCD44L-selectinIntegrin

Question 2: ________ (1A, 1B, 1C, MYH1, MYH2, MYH3, MYH4, MYH6, MYH7, MYH7B, MYH8, MYH9, MYH10, MYH11, MYH13, MYH14, MYH15, MYH16)

Question 3: In these situations, talin codistributes with concentrations of integrins in the ________.
Cell (biology)Vesicle (biology)Cell nucleusCell membrane

Question 4: ________ (A1, A2, B, C1, G1, G2)

Question 5: It is capable of linking integrins to the ________ cytoskeleton either directly or indirectly by interacting with vinculin and alpha-actinin.

Question 6: [14][15][16][17] The F3 subdomain of the FERM domain contains the highest affinity integrin-binding site for ________ β tails and is sufficient to activate integrins.
CD44IntegrinL-selectinTalin protein

Question 7: Integrin receptors are involved in the attachment of adherent cells to the ________[5][6] and of lymphocytes to other cells.
Extracellular matrixCollagenHistologyElastic fiber

Question 8: [11] Finally, talin is a substrate for the calcium-ion activated protease, ________ II,[12] which is also concentrated at points of cell-substratum contact.
Caspase 2CaspaseThe Proteolysis MapCalpain

Question 9: TALIN is a high-molecular-weight ________ protein concentrated at regions of cell-substratum contact[1] and, in lymphocytes, at cell-cell contacts.

Question 10: [2][3] Talin is a ubiquitous ________ protein that is found in high concentrations in focal adhesions.
CytosolMitochondrionCell (biology)Metabolism


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