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Syk: Quiz

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Question 1: Syk plays a similar role in transmitting signals from a variety of cell surface receptors including CD74, ________, and integrins.
Immune systemToll-like receptorTLR 2Fc receptor

Question 2: These non-receptor cytoplasmic tyrosine kinases share a characteristic dual ________ separated by a linker domain.
Abl geneSH2 domainJanus kinase 2Grb2

Question 3: SYK, along with ________, is a member of the Syk family of tyrosine kinases.
Abl geneSrc (gene)Epidermal growth factor receptorZAP-70

Question 4: Within B and ________ respectively, Syk and Zap-70 transmit signals from the B-Cell receptor and T-Cell receptor.
T cellRegulatory T cellCytotoxic T cellT helper cell

Question 5: Spleen tyrosine kinase, also known as Syk, is an ________ which in humans is encoded by the SYK gene.
EnzymeCofactor (biochemistry)Enzyme inhibitorProtein

Question 6: Several transforming viruses contain "Immunoreceptor Tyrosine Activation Motifs" (ITAMs) which lead to activation of Syk including ________, bovine leukemia virus, and mouse mammary tumor virus.
CytomegalovirusInfluenzaHerpes simplex virusEpstein-Barr virus







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