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Sulfasalazine: Quiz

  
  

Question 1: A study at University of Newcastle found that the drug may also act to aid the healing of ________.
CirrhosisHepatorenal syndromeHepatitisAcute liver failure

Question 2:
What is the elimination half life of Sulfasalazine?
10 mg oral 7 u2013 11 hours
~10 - 25 minutes
5-10 hours
4 to 10 hours

Question 3:
What is the chemical name of Sulfasalazine (IUPAC)
7-chloro-1--5-phenyl-3H-1,4-benzodiazepin-2-one
6-oxo-3-cyclohexa-1,4-dienecarboxylic acid
7-chloro-1--5--3H-1,4-benzodiazepin-2-one
2-5-(4-chlorobenzoyl)-1,4-dimethyl-pyrrol-2-ylacetic acid

Question 4: However, unlike ________ (another class of drug used in the treatment in inflammatory bowel disease), sulfasalazine has no immunosuppressant action.
CorticosteroidGlucocorticoidMineralocorticoidImmunosuppressive drug

Question 5: It does this via a number of mechanisms such as reducing the synthesis of inflammatory mediators known as eicosanoids and inflammatory ________.
CytokineInterleukinCD154Chemokine

Question 6: Sulfasalazine is mainly used for treatment of inflammatory bowel disease, including ________ and Crohn's disease.
Coeliac diseaseUlcerative colitisHepatitisColorectal cancer

Question 7: Antibiotics (Neomycin, Nystatin, Natamycin, Streptomycin, Polymyxin B, Paromomycin, ________, Kanamycin, Vancomycin, Colistin, Rifaximin)
ClotrimazoleMetronidazoleMiconazoleAmphotericin B
















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