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Sildenafil: Quiz

  
  
  

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Question 1:
What is the elimination half life of Sildenafil?
?
7 to 14 hours
3 to 4 hours
.1 hr

Question 2: People on ________ may experience sexual dysfunction, either as a result of their illness or as a result of their treatment.
AnxiolyticStimulantAntidepressantMirtazapine

Question 3: It was initially studied for use in hypertension (high blood pressure) and ________ (a symptom of ischaemic heart disease).
Coronary artery diseaseMyocardial infarctionAtherosclerosisAngina pectoris

Question 4:
How is Sildenafil excreted?
Fecal, and renal
?
Biliary, renal
Renal 13u201325%, biliary 50u201360%

Question 5: The first clinical trials were conducted in Morriston Hospital in ________.
NewportCardiffSwanseaWales

Question 6: [27] This study also noted a significant ________ in the control group.
AntidepressantPlaceboPharmaceutical drugNocebo

Question 7:
What is the chemical name of Sildenafil (IUPAC)
1-[4-ethoxy-3-
6-(2-Diethylamino-ethoxy)-benzothiazol-2-yl-dimethyl-amine
4-[2--1-ethoxy]-4-oxobutanoic acid
5-ethoxy-2-2-(morpholino)-ethylthiobenzimidazole

Question 8: [1] Phase I ________ under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections.
Clinical trialClinical trial protocolPlacebo-controlled studyMedical research

Question 9: ________ of 3-propylpyrazole-5-carboxylic acid ethyl ester with hot dimethyl sulfate.
Amino acidMethylationPosttranslational modificationAcetylation

Question 10: In February 2007, it was announced that ________ would try over the counter sales of Viagra in stores in Manchester, England.
Boots GroupHalfordsAlliance BootsUnited Kingdom
















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