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Remifentanil: Quiz


Question 1: Due to synergism between remifentanil and hypnotic drugs (such as ________) the dose of the hypnotic can be substantially reduced.

Question 2: It is given to patients during surgery to relieve pain and as an adjunct to an ________.
AnestheticLocal anestheticGeneral anaestheticDepressant

Question 3: Remifentanil has been used with some success to circumvent ________ in patients who are in need of pain management.

Question 4: Hence, it causes a reduction in sympathetic nervous system tone, respiratory depression and ________.
Non-steroidal anti-inflammatory drugDissociativeAnalgesicStimulant

Question 5: The drug's effects include a dose-dependent decrease in heart rate and ________ and respiratory rate and tidal volume.
Circulatory systemRenin-angiotensin systemVasodilationBlood pressure

Question 6: Clinically useful infusion rates in ________ vary but are usually 0.1-1 µg/kg/min[1].
Malignant hyperthermiaNitrous oxideKetamineGeneral anaesthesia

Question 7: It is administered in the form remifentanil hydrochloride and in adults is given as an ________ in doses ranging from 0.1 microgram per kilogram per minute to 0.5 (µg/kg)/min.
Intravenous therapyEnemaCream (pharmaceutical)Intraosseous infusion

Question 8: Unlike other synthetic opioids which are hepatically metabolised, remifentanil has an ________ linkage which undergoes rapid hydrolysis by non-specific tissue and plasma esterases.
Carboxylic acidAlkaneAlcoholEster

Question 9: Remifentanil (marketed by GlaxoSmithKline and Abbott as Ultiva) is a potent ultra short-acting synthetic opioid ________ drug.
DissociativeNon-steroidal anti-inflammatory drugStimulantAnalgesic

Question 10: Remifentanil is used for sedation as well as combined with other medications for use in ________.
Nitrous oxideGeneral anaesthesiaKetamineMalignant hyperthermia

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