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Protein synthesis inhibitor: Quiz

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Question 1: Macrolides[13][14] and ________[13][14] (both also having other potential mechanisms) cause premature dissociation of the peptidyl-tRNA from the ribosome.
MetronidazoleClindamycinChloramphenicolDoxycycline

Question 2: ________ prevents the turnover of elongation factor G (EF-G) from the ribosome.
ChloramphenicolNeomycinGentamicinFusidic acid

Question 3: ________[8] and macrolides[9] among other potential mechanisms of action, have evidence of inhibition of ribosomal translocation.
ClindamycinChloramphenicolLinezolidAminoglycoside

Question 4: The following antibiotics bind to the 30S subunit of the ________:
Cell (biology)RibosomeMitochondrionCell nucleus

Question 5: ________,[11] among other potential mechanisms.
DoxycyclineMetronidazoleClindamycinChloramphenicol

Question 6: [10] Quinupristin binds to binds to a nearby site on the 50S ribosomal subunit and prevents elongation of the ________,[10] as well as causing incomplete chains to be released.
Melanotan IIAfamelanotideBremelanotidePeptide

Question 7: ________ such as ricin also function via protein synthesis inhibition.
NeurotoxinAflatoxinToxinHemotoxin

Question 8: ________ blocks the peptidyl transfer step of elongation on the 50s ribosomal subunit in both bacteria and mitochondria.
ClindamycinTetracyclineOxytetracyclineChloramphenicol

Question 9: ________ and Tigecycline[7] (a glycylcycline related to tetracyclines) block the A site on the ribosome, preventing the binding of aminoacyl tRNAs.
ChloramphenicolDoxycyclineTetracycline antibioticsMinocycline

Question 10: Rifampicin inhibits prokaryotic DNA transcription into mRNA by inhibiting DNA-dependent ________ by binding its beta-subunit.
RNA polymeraseRNA-dependent RNA polymeraseRNA polymerase IITelomerase







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