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Promoter: Quiz

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Question 1: Eukaryotic promoter regulatory sequences typically bind proteins called ________ which are involved in the formation of the transcriptional complex.
Transcription factor II DGeneral transcription factorTranscription factor II FTranscription factor

Question 2: Not listed here are the many kinds of ________ that involve aberrant changes in transcriptional regulation owing to the creation of chimeric genes through pathological chromosomal translocation.
ChemotherapyMetastasisCarcinogenesisCancer

Question 3: The binding of a promoter sequence (P) to a sigma factor-________ complex (R) is a two-step process:
TelomeraseRNA polymeraseRNA-dependent RNA polymeraseRNA polymerase II

Question 4: In genetics, a promoter is a region of ________ that facilitates the transcription of a particular gene.
ProteinNucleic acidDNARNA

Question 5: In bacteria, the promoter is recognized by RNA polymerase and an associated sigma factor, which in turn are often brought to the promoter DNA by an activator protein binding to its own ________ nearby.
GenBankTranscription factorSequence motifDNA binding site

Question 6: This is a list of diseases that evidence suggests have some involvement of promoter malfunction, either through direct ________ of a promoter sequence or mutation in a transcription factor or transcriptional co-activator.
EvolutionPopulation geneticsSpeciationMutation

Question 7: ________ promoters are extremely diverse and are difficult to characterize.
ProtistFungusEukaryotePlant

Question 8: Promoter (Pribnow box, TATA box, BRE, CAAT box) - ________ (gal operon, lac operon, trp operon) - Terminator - Enhancer - Insulator - Repressor (lac repressor, trp repressor) - Silencer - Histone methylation
OperonGene expressionTranscription (genetics)Prokaryotic transcription

Question 9: Promoters contain specific DNA sequences and response elements which provide a binding site for RNA polymerase and for proteins called ________ that recruit RNA polymerase.
General transcription factorTranscription factor II FTranscription factor II DTranscription factor

Question 10: Recent evidence also indicates that several genes (including the proto-oncogene ________) have G-quadruplex motifs as potential regulatory signals.
C-junMycRetinoblastoma proteinC-Fos







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