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Primary amoebic meningoencephalitis: Quiz

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Question 1: The success rate in treating PAM is usually quite poor, since by the time of definitive diagnosis most patients have already manifested signs of terminal cerebral ________.
AutopsyHistopathologyNecrosisInflammation

Question 2: This extreme morbidity is largely blamed on the unusually non-suggestive symptomology of the early-stage disease compounded by the necessity of microbial culture of the ________ to effect a positive diagnosis.
MeningesArachnoid granulationChoroid plexusCerebrospinal fluid

Question 3: Death usually occurs within 14 days of exposure as a result of respiratory failure when the infection spreads to the ________, destroying the autonomic nerve cells of the medulla oblongata.
BrainstemHuman brainWhite matterGrey matter

Question 4: ________ has also been used with amphotericin B in successful treatment.
RifabutinDapsoneAldesulfone sodiumRifampicin

Question 5: Primary amoebic meningoencephalitis (PAM, or PAME) is a disease of the central nervous system caused by infection from ________.
ExcavateTrichomonas vaginalisNaegleria fowleriDientamoeba fragilis







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