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Pimozide: Quiz

  

Question 1: Nefazodone, ________ and Vetoconazol all lead to increased pimozide plasma levels and to a higher incidence of (potentially serious) side-effects of pimozide.
ErythromycinClindamycinClarithromycinAzithromycin

Question 2: In particular, pimozide is known for causing the unpleasant extrapyramidal side-effect ________ (commonly referred to as "restless pacing") in a large percentage of those who take it.
AkathisiaMigraineRestless legs syndromeDementia with Lewy bodies

Question 3: It has a high potency compared to ________ (ratio 50-70:1).
AmoxapineClozapineChlorpromazineQuetiapine

Question 4: The side effects include ________, tardive dyskinesia, and, more rarely, neuroleptic malignant syndrome and long QT syndrome.
MigraineAkathisiaRestless legs syndromeDementia with Lewy bodies

Question 5: Pimozide (Orap) is an ________ drug of the diphenylbutylpiperidine class.
OlanzapineAntipsychoticChlorpromazineAntiparkinson

Question 6: On a weight basis it is even more potent than ________.
ChlorpromazineRisperidoneHaloperidolClozapine

Question 7: Use as a ________ inhibitor has been described.
Listeria monocytogenesTuberculosisPathogenic bacteriaListeriosis

Question 8: It also has special neurologic indications for ________ and resistant tics.
Tic disorderTourette syndromeMajor depressive disorderAsperger syndrome

Question 9: Pimozide is used in its oral preparation in schizophrenia and chronic ________ (on-label indications in Europe only), Tourette syndrome and resistant tics (Europe, USA and Canada).
PsychiatryPsychosisEating disordersMajor depressive disorder
















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