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Parkinson's disease: Quiz


Question 1: ________, is a natural source of therapeutic quantities of L-dopa, and has been under some investigation.
Flowering plantMucuna pruriensBufoteninNicotine

Question 2: Parkinson's disease was then known as paralysis agitans, the term "Parkinson's disease" being coined later by ________.
Tourette syndromeSamuel JohnsonJean-Martin CharcotGeorges Gilles de la Tourette

Question 3: [1] ________ is the most apparent and well-known symptom.
DyskinesiaHemiballismusRestless legs syndromeTremor

Question 4: This ________ accumulation forms proteinaceous cytoplasmic inclusions called Lewy bodies.

Question 5: These neurons project to the ________ and their loss leads to alterations in the activity of the neural circuits within the basal ganglia that regulate movement, in essence an inhibition of the direct pathway and excitation of the indirect pathway.
Medial globus pallidusStriatumLateral globus pallidusThalamocortical radiations

Question 6: [31] Unlike other non selective ________, tyramine-containing foods do not cause a hypertensive crisis.
Monoamine oxidase inhibitorTricyclic antidepressantTetracyclic antidepressantPardoprunox

Question 7: ________ may be mistaken for Parkinson's disease, but lacks all other features besides tremor, and has particular characteristics distinguishing it from Parkinson's disease, such as improvement with beta blockers and alcoholic beverages.
Essential tremorMigraineEpilepsySyringomyelia

Question 8: The symptoms of Parkinson's disease result from the greatly reduced activity of pigmented ________-secreting (dopaminergic) cells in the pars compacta region of the substantia nigra (literally "black substance").

Question 9: The term Parkinsonism is used for symptoms of tremor, stiffness, and slowing of movement caused by loss of ________.

Question 10: The most likely mechanism is generation of ________.
Oxidative stressAntioxidantMetabolismReactive oxygen species

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