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Oxcarbazepine: Quiz


Question 1:
How is Oxcarbazepine excreted?
Renal 40u201350% ,

Question 2:
What is the elimination half life of Oxcarbazepine?
1-5 hours
1-2 months
biphasic: 10 min, 1-3 hr
1 to 2.5h

Question 3:
What is the chemical name of Oxcarbazepine (IUPAC)
10,11-dihydro- 10-oxo- 5H-dibenzazepine- 5-carboxamide

Question 4: It can also cause ________ (2.7% of patients), so blood sodium levels should be tested if the patient complains of severe fatigue.
DehydrationHypokalemiaDiabetic ketoacidosisHyponatremia

Question 5: This difference helps reduce the impact on the liver of metabolizing the drug, and also prevents the serious forms of ________ or agranulocytosis occasionally associated with carbamazepine.
Pernicious anemiaIron deficiency anemiaAnemiaAplastic anemia

Question 6: Oxcarbazepine is an ________ and mood stabilizing drug, used primarily in the treatment of epilepsy.

Question 7: Aside from this reduction in side effects, it is thought to have the same mechanism as carbamazepine - ________ inhibition (presumed to be the main mechanism of action) - and is generally used to treat the same conditions.
Potassium channelIon channelStretch-activated ion channelSodium channel

Question 8: Also, in treatment of ________, it appears to be effective in about one half of patients and be well tolerated.
Schizoaffective disorderBipolar disorderMajor depressive disorderMania

Question 9: In treatment of ________, oxcarbazepine has recently been found to be associated with a greater enhancement in mood and reduction in anxiety symptoms than other drugs employed to treat epilepsy.
Generalised epilepsyEpilepsyLafora diseasePartial seizure

Question 10: Oxcarbazepine is marketed as Trileptal by ________ and in Egypt and available in some countries as a generic drug.
NestléSyngentaNovartisHoffmann–La Roche

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