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Oligodendrocyte: Quiz

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Question 1: Diseases that result in injury to the oligodendroglial cells include demyelinating diseases such as ________ and leukodystrophies.
Multiple sclerosisNeuromyelitis opticaPoser criteriaAcute disseminated encephalomyelitis

Question 2: Myelin also increases impulse speed as saltatory propagation of ________ occurs at the nodes of Ranvier in between Schwann cells (of the PNS) and oligodendrocytes (of the CNS).
NeuronPhotoreceptor cellAction potentialIon channel

Question 3: Oligodendroglia are also susceptible to infection by the JC virus, which causes ________ (PML), a condition which specifically affects white matter, typically in immunocompromised patients.
PoliomyelitisTropical spastic paraparesisHerpesviral encephalitisProgressive multifocal leukoencephalopathy

Question 4: Their main function is the insulation of ________ (the long projection of nerve cells) in the central nervous system (the brain and spinal cord) of higher vertebrates.
Alpha motor neuronNeuronSchwann cellAxon

Question 5: In the rat forebrain, the majority of oligodendroglial progenitors arise during late embryogenesis and early postnatal development from cells of the ________ (SVZ) of the lateral ventricles.
Subventricular zoneNeuronMicrogliaGlial cell

Question 6: (The same function is performed by Schwann cells in the ________).
Brachial plexusAutonomic nervous systemSpinal cordPeripheral nervous system

Question 7: Additionally, the nervous system of mammals depends crucially on myelin sheaths which reduce ion leakage and decrease the capacitance of the ________.
Vesicle (biology)Cell membraneCell nucleusCell (biology)

Question 8: They are a variety of neuroglia (specifically, a sub-type of ________).
MicrogliaGlial cellAstrocyteSchwann cell

Question 9: It has been suggested that some undergo ________ [6] and others fail to differentiate into mature oligodendroglia but persist as adult oligodendroglial progenitors [7].
ApoptosisApoptosis-inducing factorTranscription factorSignal transduction

Question 10: A single oligodendrocyte can extend its processes to 50 ________, wrapping around approximately 1 mm of myelin sheath around each axon; Schwann cells, on the other hand, can only wrap around 1 axon.
Nervous systemSchwann cellNeuronAxon







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