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Olanzapine: Quiz

  
  

Question 1:
What is the melting point of Olanzapine?
195
76
117
110

Question 2:
What is the chemical name of Olanzapine (IUPAC)
2-methyl-4--10H-thieno2,3-b1,5benzodiazepine
tetrahydro-1,2,4triazolo4,5-apyridine
9-nitro- 6-phenyl- 2,5-diazabicyclo 5.4.0 undeca- 5,8,10,12- tetraen- 3-one
?

Question 3: The Food and Drug Administration requires all atypical antipsychotics to include a warning about the risk of developing hyperglycemia and ________, both of which are factors in the metabolic syndrome.
Diabetic ketoacidosisDiabetes mellitus type 1Diabetic retinopathyDiabetes mellitus

Question 4:
How is Olanzapine excreted?
Urine, Feces
urine 57%, feces 30%
80% in metabolized state: 30% biliary and 50% renal
50% in urine, 40% in feces

Question 5:
What is the molecular weight of Olanzapine?
312.439
1148.403 g/mol
Approximately 27.2 kDa
301.72438 g/mol

Question 6:
Olanzapine, Sildenafil and Ciprofloxacin are all:
Piperazines Eli Lilly and Company Thienobenzodiazepines All pages needing cleanup

Question 7: It may involve antagonism at ________ receptors.
TryptamineDimethyltryptamineBufoteninSerotonin

Question 8: ________ inability to remain still[20]
Dementia with Lewy bodiesAkathisiaRestless legs syndromeMigraine

Question 9: Endocrine side effects have included hyperprolactinemia, hyperglycemia, and ________
Diabetic retinopathyDiabetes mellitusDiabetic ketoacidosisDiabetes mellitus type 1

Question 10: Olanzapine is metabolized by the ________ system isoenzymes 1A2 and 2D6 (minor pathway).
21-HydroxylaseCYP3A4AromataseCytochrome P450
















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