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Nitric oxide: Quiz


Question 1: Phagocytes are armed with inducible nitric oxide synthase (iNOS), which is activated by ________ (IFN-γ) as a single signal or by tumor necrosis factor (TNF) along with a second signal.
Interferon alfa-2bInterferon-gammaInterferon beta-1bPeginterferon alfa-2a

Question 2: When exposed to oxygen, NO is converted into ________.
Nitrous oxideNitrogen dioxideDinitrogen tetroxideNitric oxide

Question 3: Humans with ________, diabetes, or hypertension often show impaired NO pathways.
AtheromaAortic dissectionCardiovascular diseaseAtherosclerosis

Question 4: NO forms complexes with all ________ to give complexes called metal nitrosyls.
Periodic tableActinoidNoble gasTransition metal

Question 5: It is a key ________ biological messenger, playing a role in a variety of biological processes.

Question 6: The endothelium (inner lining) of blood vessels uses nitric oxide to signal the surrounding ________ to relax, thus resulting in vasodilation and increasing blood flow.
Smooth muscleCardiac muscleIntrafusal muscle fiberSkeletal muscle

Question 7: In contrast, inhaled nitric oxide has been shown to help survival and recovery from ________ poisoning, which produces lung tissue-damaging superoxide and hinders NOS metabolism.

Question 8: One of the few practical methods is spin trapping of nitric oxide with iron-dithiocarbamate complexes and subsequent detection of the mono-nitrosyl-iron complex with ________ (EPR).
SpectroscopyNMR spectroscopyElectron paramagnetic resonanceMössbauer spectroscopy

Question 9: This reaction also produces ________ (chemiluminescence), which can be measured with a photodetector.

Question 10: [20] Because nitric oxide might serve as an inflammometer in conditions like ________, there has been increasing interest in the use of exhaled nitric oxide as a breath test in diseases with airway inflammation.
AsthmaHypersensitivity pneumonitisFarmer's lungAllergic bronchopulmonary aspergillosis

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