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Nicotinic acetylcholine receptor: Quiz


Question 1: On the other hand, the entry of calcium acts, either directly or indirectly, on different intracellular cascades leading, for example, to the regulation of the activity of some ________ or the release of neurotransmitters.

Question 2: This activation of receptors by nicotine modifies the state of ________ through two main mechanisms.
NeuronGlial cellNervous systemPhotoreceptor cell

Question 3: [1] The neuronal receptors are found in the ________ and the peripheral nervous system.
White matterCentral nervous systemAlpha motor neuronGrey matter

Question 4: On one hand, the movements of ________ cause a depolarisation of the plasma membrane (which results in an excitatory postsynaptic potential in neurons), but also by the activation of other voltage-gated ion channels.
Lithium-ion batteryIonHalf cellElectrolyte

Question 5: In contrast, paracrine transmission (volume transmission) involves ________ released by synaptic buttons, which then diffuse through the extra-cellular medium until they reach their receptors, which may be distant.

Question 6: These receptors, with highly variable kinetic, ________ and pharmacological properties, respond differently to nicotine, at very different effective concentrations.
NeuronAction potentialElectrophysiologyBrain

Question 7: Opening of the channel allows positively charged ________ to move across it, in particular, sodium enters the cell and potassium exits.
Lithium-ion batteryElectrolyteIonHalf cell

Question 8: However, whereas muscarinic receptors are also activated by muscarine, nicotinic receptors are also opened by ________.
Nicotinic agonistLobelinePhencyclidineNicotine

Question 9: In both muscle type and neuronal type receptors, the subunits are somewhat similar to one another, especially in the ________ regions.
HydrophileChemical polarityHydrophobeSuperhydrophobe

Question 10: Prolonged or repeat exposure to a stimulus often results in decreased responsiveness of that receptor toward a stimulus, termed desensitisation (for example: ________).
Coeliac diseaseSystemic lupus erythematosusMyasthenia gravisAsthma


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