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Nalmefene: Quiz


Question 1: Nalmefene is an opiate derivative similar in both structure and activity to the opiate antagonist ________.

Question 2: Nalmefene differs from naltrexone by substitution of the ________ group at the 6-position of naltrexone with a methylene (CH2) group, which considerably increases binding affinity to the μ-opioid receptor.

Question 3: Nalmefene (Revex) is an opioid receptor antagonist used primarily in the management of ________ dependence, and also has been investigated for the treatment of other addictions such as pathological gambling and addiction to shopping.

Question 4: As with other drugs of this type, nalmefene can precipitate acute withdrawal symptoms in patients who are dependent on opioid drugs, or more rarely when used post-operatively to counteract the effects of strong opioids used in ________.
NeurosurgeryICD-9-CM Volume 3Cardiothoracic surgerySurgery

Question 5: Common: drowsiness, ________, tachycardia, dizziness, nausea, vomiting
Essential hypertensionAortic dissectionAtherosclerosisHypertension

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