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Nadolol: Quiz

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Question 1: patients with ________ or myocardial infarct) should avoid nadolol as it inhibits sympathetic function.
Heart failureAtrial fibrillationCoronary artery diseaseHypertrophic cardiomyopathy

Question 2: Patients whose heart rate is largely mediated by the ________ (e.g.
Sympathetic nervous systemParasympathetic nervous systemAutonomic nervous systemNerve

Question 3: Because of its beta-2 activity, nadolol causes pulmonary bronchoconstriction and should be avoided in ________ patients in preference of a beta-1 blocker.
Allergic bronchopulmonary aspergillosisHypersensitivity pneumonitisFarmer's lungAsthma

Question 4: Nadolol is polar and hydrophilic, with low ________ solubility.
CarbohydrateSteroidMetabolismLipid

Question 5: Inhibition of beta-1 receptors in the juxtaglomerular apparatus of the ________ inhibits the renin-angiotensin system, causing a decrease in vasoconstriction and a decrease in water retention.
Endocrine systemLiverKidneyUrinary system

Question 6: Nadolol is a non-selective ________; that is, it non-selectively blocks both beta-1 and beta-2 receptors.
Beta blockerGuanethidineAntianginalClonidine

Question 7: Its inhibition of beta-2 receptors, which are mainly located in the bronchial smooth muscle of the airways, leads to airway constriction similar to that seen in ________.
Allergic bronchopulmonary aspergillosisHypersensitivity pneumonitisAsthmaFarmer's lung

Question 8: It has a preference for beta-1 receptors, which are predominantly located in the heart, thereby inhibiting the effects of catecholamines and causing a decrease in heart rate and ________.
VasodilationRenin-angiotensin systemBlood pressureCirculatory system







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