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Morphine: Quiz

  
  
  
  

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Question 1: ________ (due to accumulation of the metabolites morphine-3-glucuronide and morphine-6-glucuronide)
Nephrotic syndromeAcute kidney injuryRenal failureChronic kidney disease

Question 2: Morphine is the principal alkaloid in raw opium and constitutes ~8-19% of ________ by dry weight (depending on growing conditions) [42].
HeroinOpiumOxycodoneOpioid

Question 3:
What is the elimination half life of Morphine?
3 to 6 hours in amniotic fluid, less than 1 minute in blood plasma
60-80% in 72 hours
12 days - Multiple Dose; 120-170 hours - Single Dose
2u20133 h

Question 4: However, recent studies have been able to show some impairments caused by morphine, which is not surprising given that morphine is a ________ depressant.
NeuronGrey matterWhite matterCentral nervous system

Question 5: for ________ (i.e., to alleviate pain without curing the underlying reason for it, usually because the latter is found impossible)
CancerHospiceAdverse effectPalliative care

Question 6: In ________, morphine is classified as a Schedule 8 drug under the variously titled State and Territory Poisons Acts.
United KingdomBarbadosAustraliaCanada

Question 7: These μ-binding sites are discretely distributed in the human brain, with high densities in the posterior ________, hypothalamus, thalamus, nucleus caudatus, putamen, and certain cortical areas.
Anterior olfactory nucleusOlfactory bulbHippocampal formationAmygdala

Question 8:
What is the chemical name of Morphine (IUPAC)
-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine
?
6-amino- 2-- 3- quinazolin- 4-one
4,5-epoxy-17-methylmorphinan-3,6-diol

Question 9: Tranquilizers like alcohol (ethanol), gamma-Hydroxybutyrate (G, GHB), ________, benzodiazepines, and nonbenzodiazepines
BarbituratePropofolBarbexacloneGABAA receptor

Question 10: severe chronic pain, e.g., ________[14]
MetastasisCancerCarcinogenesisChemotherapy
















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