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Metformin: Quiz


Question 1: The benefit of metformin in NAFLD has not been extensively studied and may be only temporary;[31] although some ________ have found significant improvement with its use, the evidence is still insufficient.
Blind experimentOdds ratioRandomized controlled trialCrossover study

Question 2: The most common symptoms following overdose appear to include vomiting, ________, abdominal pain, tachycardia, drowsiness, and hyperglycemia.
NauseaDiarrheaTraveler's diarrheaGastroenteritis

Question 3:
What is the molecular weight of Metformin?
212.227 g/mol
518.05 g/mol
165.63 g/mol

Question 4:
How is Metformin excreted?
Active renal tubular excretion by OCT2
Renal: 93%

Question 5: Metformin helps reduce LDL cholesterol and ________ levels and is not associated with weight gain, and is the only anti-diabetic drug that has been conclusively shown to prevent the cardiovascular complications of diabetes.
Fatty acidTriglycerideLipidMetabolism

Question 6:
What is the chemical name of Metformin (IUPAC)
N,N-dimethylimidodicarbonimidic diamide

Question 7: When prescribed appropriately, metformin causes few adverse effects—the most common is gastrointestinal upset—and, unlike many other anti-diabetic drugs, does not cause ________ if used alone.
HypoglycemiaEpinephrineICD-10 Chapter IV: Endocrine, nutritional and metabolic diseasesDiabetes mellitus

Question 8: In this group, over 10 years of treatment, metformin reduced diabetes complications and overall mortality by about 30% when compared with ________ and sulfonylureas (glibenclamide and chlorpropamide) and by about 40% when compared with the group only given dietary advice.
AdiponectinInsulinEndocrine systemGlucagon

Question 9: A large case-control study conducted at ________ has suggested that metformin may protect against pancreatic cancer.
Alief, HoustonUniversity of Texas M. D. Anderson Cancer CenterBaylor College of MedicineHouston

Question 10: [26] It is also not associated with weight gain, and modestly reduces LDL and ________ levels.
LipidTriglycerideFatty acidCholesterol

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