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Memantine: Quiz

  

Question 1: Memantine is the first in a novel class of Alzheimer's disease medications acting on the ________ by blocking NMDA glutamate receptors.
DizocilpineNitrous oxideGlutamineGlutamic acid

Question 2:
What is the molecular weight of Memantine?
179.3 g/mol
269.345 g/mol
146.091 kDa
359.4

Question 3:
How is Memantine excreted?

Question 4:
What is the chemical name of Memantine (IUPAC)
3,5-dimethyl-tricyclo[3.3.1.13,7]decyl amine
-3--8-ethyl-
-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine
N--N′,N′-dimethyl-N-pyridin-2-ylethane-1,2-diamine

Question 5:
Memantine, Tramadol and Ketamine are all:
Antiparkinsonian agents Amines NMDA receptor antagonists Antidementia agents

Question 6: [4] Common ________ (≥1% of patients) include: confusion, dizziness, drowsiness, headache, insomnia, agitation, and/or hallucinations.
BenzodiazepineAntidepressantSelective serotonin reuptake inhibitorAdverse drug reaction

Question 7: Less common adverse effects include: vomiting, anxiety, hypertonia, cystitis, and increased ________.
LibidoCarl JungDefence mechanismPsyche (psychology)

Question 8:
Memantine, Amantadine and Selegiline are all:
NMDA receptor antagonists Amines Antiparkinsonian agents Antidementia agents

Question 9: A dysfunction of glutamatergic neurotransmission, manifested as neuronal ________, is hypothesized to be involved in the etiology of Alzheimer's disease.
Glutamate receptorExcitotoxicityGlutamic acidHuntington's disease

Question 10: Targeting the glutamatergic system, specifically ________, offers a novel approach to treatment in view of the limited efficacy of existing drugs targeting the cholinergic system.
Glutamate receptor5-HT receptor5-HT3 receptorNMDA receptor
















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