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Lupus anticoagulant: Quiz

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Question 1: Conceptually, lupus anticoagulants overlap with the ________.
Thrombotic thrombocytopenic purpuraVon Willebrand diseaseThrombophiliaAntiphospholipid syndrome

Question 2: Treatment for a lupus anticoagulant is usually undertaken in the context of documented ________, such as extremity phlebitis or dural sinus vein thrombosis.
Cerebral venous sinus thrombosisThrombosisLymphedemaDeep vein thrombosis

Question 3: Patients with a lupus anticoagulant are prone to ________, excess bleeding, and habitual abortion (repeated miscarriages).
ThrombosisLymphedemaCerebral venous sinus thrombosisDeep vein thrombosis

Question 4: Since interactions between the cell membrane and ________ are necessary for proper functioning of the coagulation cascade, the lupus anticoagulant can interfere with blood clotting as well as in-vitro tests of clotting function.
FibrinolysisPlateletCoagulationTissue plasminogen activator

Question 5: Patients with no history of ________ and a lupus anticoagulant should probably be observed.
Deep vein thrombosisLymphedemaCerebral venous sinus thrombosisThrombosis

Question 6: Lupus anticoagulant (also known as lupus antibody, LA, or lupus inhibitors) is a medical phenomenon where ________ bind to phospholipids and proteins associated with the cell membrane.
Cell-mediated immunityAutoimmunityInflammationAutoantibody

Question 7: Lupus anticoagulants can be understood as the tendency of ________ to prolong the clotting times, especially in phospholipid rich clotting testing such as the dilute Russell's viper venom time.
ThrombophiliaAntiphospholipid syndromeThrombotic thrombocytopenic purpuraVon Willebrand disease

Question 8: Paradoxically, lupus anticoagulants are also risk factors for ________.
Cerebral venous sinus thrombosisLymphedemaDeep vein thrombosisThrombosis







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