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Lofexidine: Quiz


Question 1: Lofexidine is an alpha2-adrenergic receptor agonist, historically used as a short-acting ________, but more commonly used to alleviate physical symptoms of heroin and opiate withdrawal.
Angiotensin II receptor antagonistDiureticBeta blockerAntihypertensive drug

Question 2: Lofexidine is also commonly used in conjunction with the opioid receptor antagonist ________ in rapid detoxification cases.

Question 3: Lofexidine is structurally analogous to ________, another alpha2-adrenergic receptor agonist used for treatment of opioid withdrawal symptoms.

Question 4: In the ________, the hydrochloride form, lofexidine HCl, has been licensed and sold since 1992 for opiate withdrawal relief in tablet form as BritLofex by Britannia Pharmacuetical.
CanadaEnglandWalesUnited Kingdom

Question 5: Both contain an ________ ring and a 2,6-dichlorinated phenyl ring.
Salicylic acidImidazoleBenzimidazoleSodium thiosulfate

Question 6: Lofexidine is not currently available in the ________.
PhilippinesAlaskaCanadaUnited States

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