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Ligand-gated ion channel: Quiz


Question 1: Ligand-Gated Ion Channel database at ________.
EnsemblWellcome Trust Genome CampusBioModels DatabaseEuropean Bioinformatics Institute

Question 2: LGICs are also different from voltage-gated ion channels (which open and close depending on membrane potential), and stretch-activated ion channels (which open and close depending on mechanical deformation of the ________).
Cell nucleusCell membraneCell (biology)Vesicle (biology)

Question 3: The ________ is regulated by a ligand and is usually very selective to one or more ions like Na+, K+, Ca2+, or Cl-.
Potassium channelLigand-gated ion channelIon channelSodium channel

Question 4: With a sufficient number of channels opening at once, the intracellular Na+ concentration rises to the point at which the positive charge within the cell is enough to depolarize the membrane, and an ________ is initiated.
Photoreceptor cellIon channelNeuronAction potential

Question 5: Many LGICs are additionally modulated by ________ ligands, by channel blockers, ions, or the membrane potential.
Allosteric regulationEnzyme inhibitorEnzymeProtein

Question 6: It consists of a pentamer of protein subunits, with two binding sites for ________, which, when bound, alter the receptor's configuration and cause an internal pore to open.
KetamineKynurenic acidDextromethorphanAcetylcholine

Question 7: ATP-gated channels open in response to binding the ________ ATP.
PurineAdenosine monophosphateAdenineNucleotide

Question 8: [7][8] In particular, the GABA and NMDA receptors are affected by ________ agents at concentrations similar to those used in clinical anaesthesia.
General anaestheticAnestheticLocal anestheticDepressant

Question 9: Such receptors located at synapses convert the chemical signal of presynaptically released neurotransmitter directly and very quickly into a ________ electrical signal.
NeuronPhotoreceptor cellNeuromuscular junctionChemical synapse

Question 10: They are a group of transmembrane ________ that are opened or closed in response to the binding of a chemical messenger (i.e., a ligand),[1] such as a neurotransmitter.
Ligand-gated ion channelIon channelPotassium channelSodium channel


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