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Lactate dehydrogenase: Quiz


Question 1: In ________, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis.
PhysicianSurgeryMedicineSpecialty (medicine)

Question 2: Two of them are ________-dependent enzymes with each acting on either D-lactate (EC or L-lactate (EC
Caspase 3Cytochrome cBH3 interacting domain death agonistCaspase 8

Question 3: A blood sample that has been handled incorrectly can show false-positively high levels of LDH due to ________ damage.
Red blood cellBlood plasmaHematologyPlatelet

Question 4: Measuring LDH in fluid aspirated from a ________ (or pericardial effusion) can help in the distinction between exudates (actively secreted fluid, e.g.
PneumothoraxPleurisyPleural effusionPneumonia

Question 5: A LDH-1 level higher than the LDH-2 level (a "flipped pattern"), suggests ________ (damage to heart tissues releases heart LDH, which is rich in LDH-1, into the bloodstream).
Ischaemic heart diseaseHeart failureMyocardial infarctionCoronary artery disease

Question 6: Lactate dehydrogenase (LDH or LD) is an ________ (EC present in a wide variety of organisms, including plants and animals.
Enzyme inhibitorCofactor (biochemistry)EnzymeProtein

Question 7: The enzyme is also found in ________ where high levels of lactate dehydrogenase in cerebrospinal fluid are often associated with bacterial meningitis.
Arachnoid granulationMeningesCerebrospinal fluidChoroid plexus

Question 8: The M subunit is encoded by LDHA, located on ________ 11p15.4 (Online 'Mendelian Inheritance in Man' (OMIM) 150000)
Chromosomal translocationKaryotypeChromosomeAutosome

Question 9: It converts pyruvate, the final product of ________ to lactate when oxygen is absent or in short supply, and it performs the reverse reaction during the cori cycle in the liver.
GlycolysisCarbohydrate metabolismMetabolismGluconeogenesis

Question 10: due to ________) or transudates (passively secreted fluid, due to a high hydrostatic pressure or a low oncotic pressure).
InflammationVasculitisLeukocyte extravasationMeningitis


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