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L-DOPA: Quiz

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Question 1:
What is the chemical name of L-DOPA (IUPAC)
3--N-methylpropan-1-amine
8-azabicyclo3.2.1octane
propanoic acid
3--2-methylquinazolin-4-one

Question 2: ________, or velvet bean), and is synthesized from the essential amino acids L-phenylalanine (PHE) and L-tyrosine (TYR) in the mammalian body and brain.
NicotineMucuna pruriensBufoteninFlowering plant

Question 3:
How is L-DOPA excreted?
feces
50% excreted unchanged in urine
Urine, within 24 hours
renal 70u201380%

Question 4:
What is the molecular weight of L-DOPA?
266.381 g/mol
260.331 g/mol
197.19 g/mol
347.449 g/mol

Question 5: Once L-DOPA has entered the ________ (CNS), it is converted into dopamine by the enzyme aromatic L-amino acid decarboxylase (AADC), also known as DOPA decarboxylase (DDC).
NeuronGrey matterCentral nervous systemWhite matter

Question 6: Anatoxin-aBicucullineDMCMFlurothylGabazinePentetrazolPicrotoxinStrychnine________
PregabalinEthanol1,4-ButanediolThujone

Question 7: Besides the CNS, L-DOPA is also converted into dopamine from within the ________ (PNS).
Brachial plexusAutonomic nervous systemSpinal cordPeripheral nervous system

Question 8: Effects on learning; there is some evidence that it improves ________, while impairing other complex functions
Psychogenic amnesiaWorking memoryExceptional memoryLong-term memory

Question 9: The most common plant source of L-DOPA marketed in this manner is ________ (Velvet Bean).
Flowering plantMucuna pruriensNicotineBufotenin

Question 10: [4] Though the drug is generally safe in humans, some researchers have reported an increase in cytotoxicity markers in ________ pheochromocytoma PC12 cell lines treated with L-DOPA.
RatPhilippinesVietnamMurinae







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