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Intermediate filament: Quiz


Question 1: IF are subcategorized into six types based on similarities in amino acid sequence and ________ structure.

Question 2: Keratin filaments in epithelial cells link to desmosomes (desmosomes connect the cytoskelton together) through plakoglobin, desmoplakin, desmogleins and desmocollins; ________ filaments are connected in a similar way in heart muscle cells.

Question 3: ________ (A1, A2, B, C1, G1, G2)

Question 4: At the ________, some keratins interact with desmosomes (cell-cell adhesion) and hemidesmosomes (cell-matrix adhesion) via adapter proteins.
Vesicle (biology)Cell membraneCell nucleusCell (biology)

Question 5: ________ IFs are structural components of the sarcomeres in muscle cells.

Question 6: They support the cellular membranes and keep some ________ in a fixed place within the cytoplasm.
Cell (biology)Cell nucleusOrganelleMitochondrion

Question 7: Laminopathies are a family of diseases caused by mutations in nuclear lamins and include ________ and various lipodystrophies and cardiomyopathies among others.
Autoimmune polyendocrine syndrome type 1Androgen insensitivity syndromeHypopituitarismProgeria

Question 8: A-type lamins are only expressed following ________.
ArchenteronCleavage (embryo)GastrulationRegional specification

Question 9: ________, the most widely distributed of all IF proteins, can be found in fibroblasts, leukocytes, and blood vessel endothelial cells.
DesminGelsolinVimentinAdenomatosis polyposis coli

Question 10: trichocytic keratins (about 13) (hair keratins) which make up ________, nails, horns and reptilian scales.
HairAbdominal hairBreastHuman skin


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