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Homeobox: Quiz


Question 1: MEIS1; MEIS2; MEIS3; MEOX1; MEOX2; MIXL1; MKX; MNX1; ________; MSX2
Retinoblastoma proteinGTF2F1NFKB1MSX1

Question 2: Most of the time, homeodomain proteins act in the ________ of their target genes as complexes with other transcription factors, often also homeodomain proteins.
Prokaryotic transcriptionDNAPromoterTranscription (genetics)

Question 3: Duplication of homeobox genes can produce new body segments, and such duplications are likely to have been important in the ________ of segmented animals.
EvolutionPopulation geneticsNatural selectionIntroduction to evolution

Question 4: TCF1; TCF2; ________; TGIF2; TGIF2LX; TGIF2LY; TITF1; TLX1; TLX2; TLX3; TSHZ1; TSHZ2; TSHZ3
C-junMothers against decapentaplegic homolog 2Homeobox protein TGIF1HDAC1

Question 5: Homeobox genes have even been found in ________, for example the unicellular yeasts, and in plants.

Question 6: It encodes a ________ domain (the homeodomain) which when expressed (e.g.

Question 7: Interestingly, there is one ________ family, the xyelid sawflies, in which both the antennae and mouthparts are remarkably leg-like in structure.

Question 8: The first vertebrate Hox gene was isolated in Xenopus by Eddy De Robertis and colleagues in 1984, marking the beginning of the young science of ________[4].
Evolutionary developmental biologyIntroduction to evolutionNatural selectionEvolution

Question 9: Polycomb-group proteins can silence the HOX genes by modulation of ________ structure.

Question 10: They were discovered independently in 1983 by Walter Jakob Gehring and his colleagues at the University of Basel, ________, and Matthew P. Scott and Amy Weiner, who were then working with Thomas Kaufman at Indiana University in Bloomington.


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