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Histamine: Quiz


Question 1:
What is the chemical name of Histamine (IUPAC)
dihydrogen dioxide

Question 2: Histaminergic action is known to modulate ________.

Question 3: [1] Histamine triggers the ________.
Leukocyte extravasationMeningitisVasculitisInflammation

Question 4: These cells, if sensitized by ________ antibodies attached to their membranes, degranulate when exposed to the appropriate antigen.
Immunoglobulin AImmunoglobulin EImmune systemImmunoglobulin G

Question 5: Histamine is derived from the decarboxylation of the ________ histidine, a reaction catalyzed by the enzyme L-histidine decarboxylase.
Amino acidL-DOPAAmino acid synthesisMetabolism

Question 6: Histamine has two basic centres, namely the aliphatic ________ and whichever nitrogen atom of the imidazole ring does not already have a proton.

Question 7: [3] Thus, histamine is normally protonated to a singly-charged ________.
IonElectrolyteLithium-ion batteryHalf cell

Question 8: Most histamine in the body is generated in granules in ________ or in white blood cells called basophils.
Basophil granulocyteMast cellGranulocyteEosinophil granulocyte

Question 9: Certain ________ and alkaloids, including such drugs as morphine, and curare alkaloids, can displace histamine in granules and cause its release.

Question 10: Another important site of histamine storage and release is the enterochromaffin-like (ECL) cell of the ________.
StomachVermiform appendixColon (anatomy)Small intestine

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