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Question 1: What type is thing is Hereditary nonpolyposis colorectal cancer?
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| Question 2: HNPCC defects in ________ lead to microsatellite instability, also known as MSI-H, which is a hallmark of HNPCC. | |||
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| Question 3: There is an ongoing controversy over the benefit of ________-based adjuvant therapies for HNPCC-related colorectal tumours, particularly those in stages I and II. | |||
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| Question 4: Genetic testing for mutations in ________ genes is expensive and time-consuming, so researchers have proposed techniques for identifying cancer patients who are most likely to be HNPCC carriers as ideal candidates for genetic testing. | |||
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| Question 5: In HNPCC, the mean age of diagnosis of gastric cancer is 56 years of age with intestinal-type ________ being the most commonly reported pathology. | |||
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| Question 6: The mean age of ________ diagnosis is 44 for members of families that meet the Amsterdam criteria. | |||
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| Question 7: HNPCC is inherited in an ________ manner. | |||
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| Question 8: In colon cancer patients, pathologists can measure microsatellite instability in colon tumor specimens, which is a surrogate marker for ________ gene dysfunction. | |||
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| Question 9: The Amsterdam clinical criteria identifies candidates for genetic testing, and ________ can make a diagnosis of Lynch syndrome. | |||
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| Question 10: Hereditary nonpolyposis colorectal cancer is responsible for approximately 2 percent to 7 percent of all diagnosed cases of ________. | |||
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