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Hepatitis C virus: Quiz

  

Question 1: For example, in ________, genotype 1a predominates followed by 1b, 2a, 2b, and 3a.
South AmericaAmericas (terminology)AmericasNorth America

Question 2: Hepatitis C virus (HCV) is a small (55-65 nm in size), enveloped, positive sense single strand ________ virus in the family Flaviviridae.
Small interfering RNANon-coding RNADNARNA

Question 3: Barriers to the study of HCV include the narrow host range of HCV, and the only animal model for HCV study is the ________.
BonoboHumanCommon ChimpanzeeChimpanzee

Question 4: [18] HCV, as with most all ________ viruses, exists as a viral quasispecies, making it very difficult to isolate a single strain or receptor type for study.
Non-coding RNADNARNASmall interfering RNA

Question 5: HCV mainly replicates within hepatocytes in the liver, although there is controversial evidence for replication in ________ or monocytes.
ThymocyteAdaptive immune systemImmune systemLymphocyte

Question 6: Hepatitis C virus has a positive sense ________ genome that consists of a single open reading frame of 9600 nucleoside bases.
RNANon-coding RNADNASmall interfering RNA

Question 7: Although ________, Hepatitis B virus, and Hepatitis C virus have similar names (because they all cause liver inflammation), these are distinctly different viruses both genetically and clinically.
AIDSInfluenzaRotavirusHepatitis A

Question 8: IV: ________ (Severe acute respiratory syndrome)
InfluenzaSARS coronavirusAIDSInfluenza A virus

Question 9: Two putative HCV receptors are ________ and human scavenger receptor class B1 (SR-BI).
TNFRSF1AMUC1CD81CDH1 (gene)

Question 10: Diagnosis of HCV can occur via ________ of the 5′-noncoding region (5′-NCR).
GeneticsGenetic discriminationCancerGenetic testing
















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