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Heparin: Quiz

  
  
  

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Question 1:
What is the elimination half life of Heparin?
1-2 hrs
114 hrs
22-60 hrs
1.5 hrs

Question 2: Test tubes, Vacutainers, and ________ tubes that use the lithium salt of heparin (lithium heparin) as an anticoagulant are usually marked with green stickers and green tops.
Circulatory systemHeartArteryCapillary

Question 3: In December 2007, the U.S. Food and Drug Administration (FDA) recalled a shipment of heparin because of bacterial growth (________) in several unopened syringes of this product.
PneumoniaMeningitisSerratia marcescensAntibiotic resistance

Question 4:
How is Heparin excreted?
?
82% urine; 12% faeces
renal
70-90% unchanged in urine, 1.3ml/kg/min t1/2 2- 4 hours

Question 5: In July 2008, another set of twins born at Christus Spohn Hospital South, a hospital located in ________, died after an accidentally administered overdose of the drug.
DallasSan AntonioCorpus Christi, TexasLaredo, Texas

Question 6:
What is the chemical name of Heparin (IUPAC)
3-{2-4-(2-methylphenyl)piperazin-1-ylethyl}-5,6,7,8-
see Heparin structure
5-(1R,2S,3S,5S)-3--8-methyl-8-azabicyclo3.2.1octan-2-yl]-3--1,2-oxazole
4-amino-5-bromo-N-2-(diethylamino)ethyl-2-methoxybenzamide

Question 7: It is known that the diprotonated form of ________ binds site specifically to heparin.
IbogaineHistamineMirtazapineAmitriptyline

Question 8: The Quaid family subsequently sued the manufacturer, ________,[58][59] and settled with the hospital for $750,000.
BoeingAbbott LaboratoriesBaxter InternationalKraft Foods

Question 9: The contaminant was identified as an "over-sulphated" derivative of chondroitin sulfate, a popular shellfish-derived supplement often used for ________.
MeningitisVasculitisArthritisHepatitis

Question 10: [46][47] In contrast heparin may inhibit ________ when it is administered in the presence of corticosteroids.
AngiogenesisVascular endothelial growth factorWound healingIntegrin
















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