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Hemolytic disease of the newborn: Quiz

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Question 1: ABO blood group system and the D antigen of the ________ typing are routine prior to transfusion.
ABO blood group systemRh blood group systemBlood typeDuffy antigen system

Question 2: Similar conditions include acquired hemolytic anemia, congenital toxoplasma and syphilis infection, congenital obstruction of the bile duct and ________ infection.
CytomegalovirusAIDSErythema infectiosumHepatitis B

Question 3: In subsequent pregnancies, if there is a similar incompatibility in the fetus, these antibodies are then able to cross the placenta into the fetal bloodstream to attach to the ________ and cause hemolysis.
Red blood cellBlood plasmaHematologyPlatelet

Question 4: Antibodies are produced when the body is exposed to an ________ foreign to the make-up of the body.
PhagocyteAntigenImmune systemPolyclonal B cell response

Question 5: Like any other severe ________, there is the possibility of acute or chronic kernicterus.
Neonatal jaundicePneumothoraxNecrotizing enterocolitisPolycythemia

Question 6: Fetal-maternal ________ can occur due to trauma, abortion, childbirth, ruptures in the placenta during pregnancy, or medical procedures carried out during pregnancy that breach the uterine wall.
BleedingBruisePurpuraGastrointestinal bleeding

Question 7: Profound anemia can cause high-output ________, with pallor, enlarged liver and/or spleen, generalized swelling, and respiratory distress.
Hypertrophic cardiomyopathyMyocardial infarctionHeart failureAtrial fibrillation

Question 8: Complications of HDN could include kernicterus, hepatosplenomegaly, inspissated (thickened or dried) bile syndrome and/or greenish staining of the teeth, ________ and damage to the liver due to excess bilirubin.
Glucose-6-phosphate dehydrogenase deficiencyHemolytic anemiaParoxysmal nocturnal hemoglobinuriaSpherocytosis

Question 9: The woman may receive a therapeutic ________.
Blood donationIntraoperative blood salvageBlood transfusionTransfusion reaction

Question 10: The three most common models in which a woman becomes sensitized toward (i.e., produces IgG ________ against) a particular antigen are:
Immune systemAntibodyAutoantibodyAdaptive immune system







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