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Group C nerve fiber: Quiz


Question 1: [2] The Remak Schwann cells have been shown to be electrochemically responsive to ________ of the axons contained within them.
NeuronIon channelPhotoreceptor cellAction potential

Question 2: [4] This hyper-excitability can be caused by an increased neuronal response to a noxious stimulus (________), a larger neuronal receptive field, or spread of the hyper-excitability to other segments.
HypoalgesiaHeadacheChronic painHyperalgesia

Question 3: ________ (axon hillock, axon terminals, axoplasm, axolemma, neurofibril/neurofilament)
AxonNeuronSchwann cellNervous system

Question 4: After a nerve lesion of either C fibers or Aδ fibers, they become abnormally sensitive and cause ________ spontaneous activity.
InfectionPathologyDiseaseInfectious disease

Question 5: [1] If damage to these heat transducer receptors occurs, the result can be chronic neuropathic pain caused by lowering the heat pain threshold for their ________.
UbiquitinPhosphorylationPosttranslational modificationAmino acid

Question 6: [4] The abnormal activity of the damaged nerves is associated with the increased presence of mRNA for voltage-gated ________.
Ion channelSodium channelStretch-activated ion channelPotassium channel

Question 7: [8] Some past treatments include opiates like poppy extract, non-steroidal anti-inflammatory drugs like salicylic acid, and ________.

Question 8: This abnormal central sensitization cycle results in increased pain (hyperalgesia) and pain responses from previously non-noxious stimuli evoke a pain response (________).
AllodyniaHeadacheNociceptorSubstance P

Question 9:
  • ________ [CRPSs][4]
    Hereditary spastic paraplegiaPeripheral neuropathyComplex regional pain syndromeTrigeminal neuralgia

Question 10: [4] The glutamate interacts with the postsynaptic ________, which aids the sensitization of the dorsal horn.
NMDA receptorGlutamate receptor5-HT receptor5-HT3 receptor


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