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Glycine receptor: Quiz

  

Question 1: [2] ________ has recently been found also to be a competitive antagonist.
MethamphetamineAmphetamineCaffeineMethylphenidate

Question 2: The receptor can be activated by a range of simple ________ including glycine, β-alanine and taurine, and can be selectively blocked by the high-affinity competitive antagonist strychnine.
L-DOPAAmino acid synthesisAmino acidMetabolism

Question 3: Strychnine-sensitive glycine receptors are members of a family of ________.
Sodium channelGeneral bacterial porin familyLigand-gated ion channelPotassium channel

Question 4: ________ have been used to track the diffusion of glycine receptors into the synapse of neurons.
Carbon nanotubeNanomaterialsQuantum dotFullerene

Question 5: Disruption of GlyR surface expression or reduced ability of expressed GlyRs to conduct chloride ions results in the rare neurological disorder, ________.
Stiff person syndromeEpilepsyClonazepamHyperekplexia

Question 6: It is one of the most widely distributed inhibitory receptors in the ________ and has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brain stem.
NeuronGrey matterWhite matterCentral nervous system

Question 7: The glycine receptor, or GlyR, is the receptor for the ________ neurotransmitter glycine.
L-DOPAAmino acidMetabolismAmino acid synthesis

Question 8: There are presently four known isoforms of the α-subunit (α1-4) of GlyR that are essential to bind ________ (GLRA1, GLRA2, GLRA3, GLRA4) and a single β-subunit (GLRB).
Crystal field theoryLigandCoordination complexHSAB theory
















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