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Glutamate receptor: Quiz


Question 1: [1] Glutamate was initially discovered to be a ________ in insect studies in the early 1960s.

Question 2: Excessive extracellular glutamate concentrations reverse xCT and glial cells no longer have enough cystine to synthesize glutathione (GSH), an ________.
MetabolismAntioxidantHuman nutritionNutrition

Question 3: Overstimulation of glutamate receptors causes neurodegeneration and neuronal damage through a process called ________.
Huntington's diseaseExcitotoxicityAlzheimer's diseaseGlutamic acid

Question 4: Glutamate receptors are synaptic receptors located primarily on the membranes of ________ cells.
NeuronPhotoreceptor cellNervous systemGlial cell

Question 5: Glutamate receptors have been found to have an influence in ischemia/stroke, ________, Parkinson's Disease, Huntington's Disease, and aching.
SymptomSeizureConvulsionICD-10 Chapter XVIII: Symptoms, signs and abnormal clinical and laboratory findings

Question 6: cerebral infarction or ________), acute neurodegeneration caused by excitotoxicity may spread to proximal neurons through two processes.
Gastrointestinal bleedingBleedingPurpuraBruise

Question 7: ________ is directly involved with spinal NMDA receptors.
HypoalgesiaHyperalgesiaHeadacheChronic pain

Question 8: Refractory schizophrenia patients showed associated improvements in both negative and positive symptoms, underscoring the potential uses of GluR antagonists as ________.

Question 9: Hypoxia and ________ trigger bioenergetic failure; mitochondria stop producing ATP energy.
HypoglycemiaICD-10 Chapter IV: Endocrine, nutritional and metabolic diseasesDiabetes mellitusEpinephrine

Question 10: Metabotropic glutamate receptors (mGluRs) indirectly activate ion-channels on the plasma membrane through a signaling cascade that involves ________.
G proteinPlasma membrane Ca2+ ATPaseRas (protein)GTPase


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