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Gluconeogenesis: Quiz


Question 1: It is one of the two main mechanisms the body uses to keep blood ________ levels from dropping too low (hypoglycemia).

Question 2: Many of the reactions are the reversible steps found in ________.
Carbohydrate metabolismGluconeogenesisGlycolysisMetabolism

Question 3: Gluconeogenesis (abbreviated GNG) is a metabolic pathway that results in the generation of glucose from non-________ carbon substrates such as lactate, glycerol, and glucogenic amino acids.

Question 4: This process occurs during periods of fasting, starvation, low-carbohydrate diets, or intense ________ and is highly endergonic.
Major depressive disorderStrength trainingPhysical exerciseObesity

Question 5: The majority of the ________ responsible for gluconeogenesis are found in the cytoplasm; the exceptions are mitochondrial pyruvate carboxylase, and, in animals, phosphoenolpyruvate carboxykinase.
Enzyme inhibitorEnzymeProteinCofactor (biochemistry)

Question 6: [2] In animals, gluconeogenesis takes place mainly in the liver and, to a smaller extent, in the cortex of ________.
KidneyImmune systemUrinary systemEndocrine system

Question 7: Gluconeogenesis is also a target of therapy for type II diabetes, such as ________, which inhibit glucose formation and stimulate glucose uptake by cells.

Question 8: The final reaction of gluconeogenesis, the formation of glucose, occurs in the lumen of the ________ where glucose-6-phosphate is hydrolyzed by glucose-6-phosphatase to produce glucose.
Endomembrane systemEndoplasmic reticulumGolgi apparatusCell (biology)

Question 9: Glucose is shuttled into the cytosol by ________ located in the membrane of the endoplasmic reticulum.
ATP-binding cassette transporterSodium-calcium exchangerNa-K-Cl cotransporterGlucose transporter

Question 10: While most steps in gluconeogenesis are the reverse of those found in ________, three regulated and strongly exergonic reactions are replaced with more kinetically favorable reactions.
GlycolysisPhosphofructokinase 1MetabolismCarbohydrate metabolism


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