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GABAA receptor: Quiz

  

Question 1: Some of the subtype-selective negative allosteric modulators such as α5IA are being investigated for their ________ effects, as well as treatments for the unwanted side effects of other GABAergic drugs.
StimulantMethamphetamineNootropicMethylphenidate

Question 2: ________ (subtype-selective partial agonist)
AlprazolamChlordiazepoxideBretazenilDiazepam

Question 3: three γ's (GABRG1, ________, GABRG3)
GRIA2GRIN2AGRIN2BGABRG2

Question 4: The ionotropic GABAA receptor protein complex is also the molecular target of the ________ (BZ) class of tranquilizer drugs.
PropofolBarbexacloneBenzodiazepineGABA reuptake inhibitor

Question 5: The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ________.
Ion channelCystic fibrosis transmembrane conductance regulatorSodium channelPotassium channel

Question 6: Upon activation, the GABAA receptor selectively conducts Cl- through its pore, resulting in hyperpolarization of the ________.
Photoreceptor cellNeuronNervous systemGlial cell

Question 7: Its endogenous ligand is γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the ________.
Grey matterNeuronCentral nervous systemWhite matter

Question 8: Some such as muscimol may also be ________.
Psychedelic drugDrugPsychedelics, dissociatives and deliriantsPsychoactive drug

Question 9: This causes an inhibitory effect on neurotransmission by diminishing the chance of a successful ________ occurring.
Action potentialNeuronPhotoreceptor cellIon channel
















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