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Fibrin: Quiz


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Question 1: It is used in ________ as an inflammatory marker: in horses a level above the normal range of 1.0-4.0 g/L suggests some degree of systemic inflammatory response.
Veterinary specialtiesVeterinary dentistryVeterinary medicineMedical school

Question 2: Excessive generation of fibrin due to activation of the coagulation cascade leads to thrombosis, while ineffective generation or premature lysis of fibrin predisposes to ________.
PurpuraBruiseGastrointestinal bleedingBleeding

Question 3: [5] Fibrin polymerization disorders can be detected by ________ methods such as thrombelastometry.
Linear elasticityViscoelasticitySolidViscosity

Question 4: Fibrin (also called Factor Ia) is a fibrous ________ involved in the clotting of blood, and is non-globular.

Question 5: It may be elevated in any form of ________, as it is an acute phase protein; for example, it is especially apparent in human gingival tissue during the initial phase of periodontal disease.
InflammationLeukocyte extravasationVasculitisMeningitis

Question 6: Processes in the ________ cascade activate the zymogen prothrombin to the serine protease thrombin, which is responsible for converting fibrinogen into fibrin.
FibrinolysisTissue plasminogen activatorCoagulationPlatelet

Question 7: Fibrinogen (also called factor I) is a 340 ________ glycoprotein synthesised in the liver by hepatocytes and megakaryocytes.
Atomic massAtomic mass unitAtomHydrogen

Question 8: [5] Higher levels are, amongst others, associated with ________ (>4.6 g/L).
PneumopericardiumCoronary artery aneurysmCardiovascular diseaseHeart disease

Question 9: [2] Both the activation of Factor XIII by thrombin and plasminogen activator (________) are catalyzed by fibrin.
StreptokinaseAncrodUrokinaseTissue plasminogen activator

Question 10: [3] Recent research has shown that fibrin plays a key role in the inflammatory response and development of ________.
Systemic lupus erythematosusRheumatoid arthritisCoeliac diseaseReactive arthritis


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