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Familial adenomatous polyposis: Quiz
  
  

Question 1: Other signs that may point to FAP are pigmented lesions of the ________ ("CHRPE - congenital hypertrophy of the retinal pigment epithelium"), jaw cysts, sebaceous cysts, and osteomata (benign bone tumors).
ScleraIris dilator muscleRetinaCiliary muscle

Question 2: If the blood is not visible, it is still possible for the patient to develop ________ due to gradually developing iron deficiency.
Aplastic anemiaAnemiaIron deficiency anemiaPernicious anemia

Question 3: ________ is possible if a disease-causing mutation is identified in an affected family member; however, prenatal testing for typically adult-onset disorders is uncommon and requires careful genetic counseling.
Prenatal diagnosisAmniocentesisChorionic villus samplingObstetric ultrasonography

Question 4: However, other tumor-suppressor functions of Apc may be related to cell adherence and ________ organization.
CytoskeletonProteinFtsZMicrotubule

Question 5: Various medications are being investigated for slowing malignant degeneration of polyps, most prominently the ________ (NSAIDs).
IbuprofenNon-steroidal anti-inflammatory drugAspirinAnalgesic

Question 6: When this condition results from mutations in the ________, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene is sufficient to cause the disorder.
DystrophinBeta-cateninGelsolinAdenomatosis polyposis coli

Question 7: Mutations in the MUTYH gene are inherited in an ________ pattern, which means two copies of the gene must be altered for a person to be affected by the disorder.
ChromosomeDominance (genetics)AlleleGenetics

Question 8: Ultrasound of the abdomen and blood tests evaluating liver function are often performed to rule out ________ to the liver.
CancerCancer stagingMetastasisHead and neck cancer

Question 9: MYH glycosylase fixes these mistakes by base excision repair, such that mutations do not accumulate in the ________ and lead to tumor formation.
DNAProteinGeneRNA

Question 10: For more information see ________.
Beta-cateninMouse models of colorectal and intestinal cancerOncogeneAdenomatosis polyposis coli
















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