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Question 1: Some patients with ovarian hyperstimulation syndrome may have ________ in the gene for FSHR making them more sensitive to gonadotropin stimulation.
EvolutionSpeciationMutationPopulation genetics

Question 2: ________ in the cell nucleus binds to phosphorylated proteins through the cyclic AMP response element (CRE) which results in the activation of genes.
RNADNANucleic acidGenetics

Question 3: The follicle stimulating hormone receptor or FSH-receptor (FSHR) is a transmembrane receptor that interacts with the follicle stimulating hormone (FSH) and represents a ________ (GPCR).
Luteinizing hormone/choriogonadotropin receptorReceptor (biochemistry)Olfactory receptorG protein-coupled receptor

Question 4: The transmembrane domain contains two highly conserved ________ residues which build disulfide bonds to stabilize the receptor structure.
MethionineSerineGlutamic acidCysteine

Question 5: A key reaction of this downregulation is the ________ of the intracellular (or cytoplasmic) receptor domain by protein kinases.
UbiquitinAmino acidPosttranslational modificationPhosphorylation

Question 6: The bound FSH-receptor complex is brought by lateral migration to a "coated pit" where such units are concentrated and then stabilized by a framework of ________.
CaveolinLysosomal trafficking regulatorClathrinCOPII

Question 7: Polymorphism may affect FSH receptor populations and lead to poorer responses in infertile women who receive FSH medication for ________.
In vitro fertilisationPregnancyAssisted reproductive technologyArtificial insemination

Question 8: In the male the FSH receptor has been identified on the Sertoli cells that are critical for ________.
SpermiogenesisReproductive systemSpermatozoonSpermatogenesis

Question 9: In turn, FSH stimulates granulosa cells to produce ________.
EstrogenEstradiolTestosteroneProgesterone

Question 10: The C-terminal domain is intracellular and brief, rich in serine and threonine residues for possible ________.
Amino acidUbiquitinPosttranslational modificationPhosphorylation
















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