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Endothelium-derived relaxing factor: Quiz


Question 1: Older candidate molecules included nitroxyl and ________.
Hydroxylammonium sulfateHydroxylamineAmmoniaHydrazine

Question 2: ________, or EDHF.
Endothelium-derived hyperpolarizing factorCytochrome P450VasodilationArachidonic acid

Question 3: EDRF was discovered and characterized by Robert F. Furchgott, a winner of the ________ in 1998 with his co-researchers Louis J. Ignarro and Ferid Murad.
Salvador LuriaNobel Prize in Physiology or MedicineBarbara McClintockStanley Cohen (biochemist)

Question 4: [6][7] There is some evidence that EDHF is ________.

Question 5: Heme proteins from blood can also stimulate the inducible isoform of Heme oxygenase (HO-1 also known as heat shock protein 32) which produces ________ that can relax smooth muscle.
Carbon monoxideNitric oxideNitrous oxideHydrogen sulfide

Question 6: It causes the ________ in the vessel wall to relax.
Smooth muscleCardiac muscleSkeletal muscleIntrafusal muscle fiber

Question 7: According to Furchgott's website at ________, "...we are investigating whether the endothelium-derived relaxing factor (EDRF) is simply nitric oxide or a mixture of substances".
Binghamton UniversityStony Brook UniversityUniversity at Albany, SUNYSUNY Downstate Medical Center

Question 8: The most well characterized is ________ (NO), and some older sources consider the two terms to be equivalent.
Carbon monoxideNitrous oxideHydrogen sulfideNitric oxide


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