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Endothelium: Quiz


Question 1: Formation of new blood vessels (________)
Vascular endothelial growth factorAngiogenesisWound healingIntegrin

Question 2: Excessive or prolonged increases in permeability of the endothelial monolayer, as in cases of chronic inflammation, may lead to tissue ________/swelling.

Question 3: [3] The signalling protein ________ is essential for maintaining normal endothelial cell function [4].

Question 4: Barrier function - the endothelium acts as a selective barrier between the vessel lumen and surrounding tissue, controlling the passage of materials and the transit of ________ into and out of the bloodstream.
Eosinophil granulocyteNeutrophil granulocyteWhite blood cellPhagocyte

Question 5: The endothelium normally provides a non-thrombogenic surface because it contains heparan sulphate which acts as a cofactor for activating ________, a protease that cleaves several factors in the coagulation cascade.
PlasminAlpha 2-antiplasminAlpha 1-antitrypsinAntithrombin

Question 6: The most prevailing mechanism of endothelial dysfunction is an increase in ________, which can impair nitric oxide production and activity via several mechanisms.
Reactive oxygen speciesMetabolismOxidative stressAntioxidant

Question 7: The endothelium is the thin layer of cells that line the interior surface of blood vessels,[1] forming an interface between circulating ________ in the lumen and the rest of the vessel wall.
Blood plasmaBloodRed blood cellPlatelet

Question 8: Endothelial tissue is a specialized type of epithelium tissue (one of the four types of ________ in animals).
Organ (anatomy)Nervous systemImmune systemTissue (biology)

Question 9: Endothelial cells line the entire circulatory system, from the heart to the smallest ________.
CapillaryVeinHuman lungArtery

Question 10: These cells reduce ________ of the flow of blood allowing the fluid to be pumped farther.
Reynolds numberFluid dynamicsTurbulenceDrag (physics)


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