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Drug design: Quiz

  
  

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Question 1: ________, the prototypical H2-receptor antagonist from which the later members of the class were developed
FamotidineH2 antagonistCimetidineRanitidine

Question 2: ________
TC-2216IsproniclineSazetidine ANicotinic agonist

Question 3: Selective COX-2 inhibitor ________
Non-steroidal anti-inflammatory drugAspirinAnalgesicAnti-inflammatory

Question 4: ________
Discovery and development of non-nucleoside reverse transcriptase inhibitorsEnfuvirtideDiscovery and development of CCR5 receptor antagonistsVicriviroc

Question 5: Drug design, also sometimes referred to as rational drug design, is the ________ process of finding new medications based on the knowledge of the biological target.
InventionDutch inventions and discoveriesEnglish inventions and discoveriesFrench inventions and discoveries

Question 6: Dorzolamide, a ________ inhibitor used to treat glaucoma
Carbonic anhydraseFumaraseCystathionine beta synthaseTryptophan synthase

Question 7: [1] The drug is most commonly an organic small molecule which activates or inhibits the function of a ________ such as a protein which in turn results in a therapeutic benefit to the patient.
Adenosine triphosphateMetabolismBiomoleculeBiochemistry

Question 8: hit identification using ________ (structure- or ligand-based design)
Docking (molecular)Virtual screeningScoring functions for dockingDrug discovery

Question 9: Typically a drug target is a key ________ involved in a particular metabolic or signaling pathway that is specific to a disease condition or pathology, or to the infectivity or survival of a microbial pathogen.
AtomMoleculeElectronNeutron

Question 10: In addition ________ based gene silencing technologies may have therapeutic applications.
Non-coding RNADNAMorpholinoMessenger RNA
















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