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Dipyridamole: Quiz


Question 1:
What is the elimination half life of Dipyridamole?
Alpha , Beta
2 to 3 hours
21-23 hours
4-5 hours in dogs, 6 hours in cats, 1.5 - 4.5 hours in sheep.

Question 2:
What is the molecular weight of Dipyridamole?
269.345 g/mol
504.626 g/mol
518.05 g/mol
1148.403 g/mol

Question 3: ________ (Bemiparin, Certoparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin)
WarfarinDirect thrombin inhibitorAnticoagulantLow molecular weight heparin

Question 4:
What is the chemical name of Dipyridamole (IUPAC)
9-nitro- 6-phenyl- 2,5-diazabicyclo 5.4.0 undeca- 5,8,10,12- tetraen- 3-one

Question 5: It also inhibits the enzyme adenosine deaminase which normally breaks down ________ into inosine.
AdenosineAdenosine diphosphateAdenosine monophosphateAdenosine triphosphate

Question 6: Dipyridamole absorption is pH-dependent and concomitant treatment with gastric acid suppressors (such as a ________) will inhibit uptake significantly.
H2 antagonistNon-steroidal anti-inflammatory drugProton-pump inhibitorH1 antagonist

Question 7: Modified release dipyridamole is used in conjunction with aspirin (under the trade names Aggrenox in the USA or Asasantin Retard in the ________) in the secondary prevention of stroke and transient ischaemic attack.
EnglandWalesUnited KingdomCanada

Question 8: Dipyridamole also has non-medicinal uses in a laboratory context, such as the inhibition of cardiovirus growth in ________.
DNACancerVirologyCell culture

Question 9: Flow heterogeneity (a necessary precursor to ischemia) can be detected with gamma cameras and ________ using nuclear imaging agents such as Thallium-201 and Tc99m-Sestamibi.
Positron emission tomographyX-raySingle photon emission computed tomographyRadiation therapy

Question 10: cAMP impairs platelet aggregation and also causes arteriolar ________ relaxation.
Cardiac muscleIntrafusal muscle fiberSkeletal muscleSmooth muscle

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