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Dextromethorphan: Quiz


Question 1: Because administration of dextromethorphan can trigger a histamine release (an ________ reaction), its use in atopic children is very limited.
AnaphylaxisHypersensitivityGraft-versus-host diseaseAllergy

Question 2: In addition, a combination of dextromethorphan and quinidine has been shown to alleviate symptoms of easy laughing and crying (pseudobulbar affect) in patients with ________ and multiple sclerosis.
Amyotrophic lateral sclerosisHuntington's diseaseAlzheimer's diseaseMotor neurone disease

Question 3: It is one of the active ingredients in many over-the-counter cold and ________ medicines, such as Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, and others, including generic labels.
CoughICD-10 Chapter XVIII: Symptoms, signs and abnormal clinical and laboratory findingsPleurisyPneumonia

Question 4:
What is the melting point of Dextromethorphan?

Question 5: [28][29] In some rare documented cases, dextromethorphan has produced ________ in some people who used it recreationally.
Drug addictionAddictionSocial anxiety disorderBenzodiazepine dependence

Question 6: Dextromethorphan is rapidly absorbed from the gastrointestinal tract and converted into the less active metabolite, dextrorphan in the liver by the cytochrome P450 enzyme ________.

Question 7: ________ (NET) blocker (norepinephrine reuptake inhibitor).
Norepinephrine transporterSerotonin transporterDopamine transporterGABA transporter 1

Question 8: Dextromethorphan (DXM or DM) is an ________ (cough suppressant) drug.
AnalgesicNon-steroidal anti-inflammatory drugCough medicineDissociative

Question 9: Dextromethorphan had been thought to cause Olney's Lesions when administered ________; however, this was later proven not to be true.
Intraosseous infusionCream (pharmaceutical)EnemaIntravenous therapy

Question 10: body rash/________ (see below)

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